Table 2 Drug likeness score of different phytochemicals predicted based on Lipinski Rule
Ligands | Solubility | Drug likeness | Drug Score |
|---|---|---|---|
Casticin | − 3.26 | 1.45 | 0.26 |
Isoorientin | − 1.97 | − 0.71 | 0.54 |
Luteolin | − 2.56 | 1.9 | 0.84 |
4-Hydroxybenzoic acid | − 1.33 | − 1.5 | 0.35 |
Chrysophanol | − 4.48 | − 1.67 | 0.16 |
Silibinin | − 3.41 | 1.64 | 0.64 |
Capecitabine | − 3.37 | − 21.3 | 0.16 |
5-Flurouracil | − 1.76 | − 4.5 | 0.06 |
Irinotecan | − 4.5 | 0.07 | 0.35 |