Table 1 Comparison of cytogenetic aberrations and the studied clinical parameters in our patients
| Â | Hyperdiploidy | P value | t(4;14) | P value | del 17 p | P value | |||
|---|---|---|---|---|---|---|---|---|---|
Negative | Positive | Negative | Positive | Negative | Positive | ||||
No. = 39 | No. = 21 | No. = 54 | No. = 6 | No. = 53 | No. = 7 | ||||
Hb (gm/dL) | |||||||||
 ≥ 10 | 9 (23.1%) | 11 (52.4%) | 0.022 | 20 (37.0%) | 0 (0.0%) | 0.068 | 20 (37.7%) | 0 (0.0%) | 0.047 |
 < 10 | 30 (76.9%) | 10 (47.6%) |  | 34 (63.0%) | 60 (100.0%) |  | 33 (62.3%) | 7 (100.0%) |  |
Creat (mg/dL) | |||||||||
 ≤ 2 | 21 (53.8%) | 16 (76.2%) | 0.090 | 35 (64.8%) | 2 (33.3%) | 0.132 | 35 (66.0%) | 2 (28.0%) | 0.055 |
 > 2 | 18 (46.2%) | 5 (23.8%) |  | 19 (35.2%) | 4 (66.7%) |  | 18 (34.0%) | 5 (71.4%) |  |
Ca (mg/dL) | |||||||||
 ≤ 11 | 25 (64.1%) | 12 (57.1%) | 0.597 | 35 (64.8%) | 2 (33.3%) | 0.132 | 37 (69.8%) | 0 (0.0%) | 0.00 |
 > 11 | 14 (35.9%) | 9 (42.9%) |  | 19 (35.2%) | 4 (66.7%) |  | 16 (30.2%) | 7 (100.0%) |  |
BJP | |||||||||
 Negative | 11 (28.2%) | 6 (28.6%) | 0.976 | 15 (27.8%) | 2 (33.3%) | 0.774 | 0 (0.0%) | 2 (28.6%) | 0.988 |
 Positive | 28 (71.8%) | 15 (71.4%) |  | 39 (72.2%) | 4 (66.7%) |  | 53 (100.0%) | 5 (71.4%) |  |
IPT | |||||||||
 Lambda | 19 (48.7%) | 5 (23.8%) | 0.060 | 21 (38.9%) | 3 (50.0%) | 0.598 | 17 (32.1%) | 7 (100.0%) | 0.001 |
 Kappa | 20 (51.3%) | 16 (76.2%) |  | 33 (61.1%) | 3 (50.0%) |  | 36 (67.9%) | 0 (0.0%) |  |
Response to treatment | |||||||||
 Non-responder | 19 (48.7%) | 2 (9.5%) | 0.002 | 18 (33.3%) | 3 (50.0%) | 0.417 | 14 (26.4%) | 7 (100.0%) | 0.00 |
 Responder | 20 (51.3%) | 19 (90.5%) |  | 36 (66.7%) | 3 (50.0%) |  | 39 (73.6%) | 0 (0.0%) |  |
ISS stage | |||||||||
 I | 15 (38.5%) | 10 (47.6%) | 0.027 | 23 (42.6%) | 2 (33.3%) | 0.083 | 25 (47.2%) | 0 (0.0%) | 0.00 |
 II | 8 (20.5%) | 9 (42.9%) |  | 17 (31.5%) | 0 (0.0%) |  | 17 (32.1%) | 0 (0.0%) |  |
 III | 16 (41.0%) | 2 (9.5%) |  | 14 (25.9) | 4 (66.7%) |  | 11 (20.8%) | 7 (100.0%) |  |
RISS stage | |||||||||
 I | 4 (10.3%) | 3 (14.3%) | 0.007 | 7 (13.0%) | 0 (0.0%) | 0.000 | 7 (13.2%) | 0 (0.0%) | 0.00 |
 II | 21 (53.8%) | 18 (85.7%) |  | 39 (72.2%) | 0 (0.0%) |  | 39 (73.6%) | 0 (0.0%) |  |
 III | 14 (35.9%) | 0 (0.0%) |  | 8 (14.8%) | 6 (100.0%) |  | 7 (13.2%) | 7 (100.0%) |  |