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Table 1 Genotype and allele frequencies for the MTHFR C677T (rs1801133) polymorphism among groups

From: MTHFR C677T (rs1801133) genetic polymorphism is associated with development risk of essential hypertension in the Turkish population

 

Genotype

Allele

χ2, df, p

TT versus CC + CT

C versus T

CC: n, %

CT: n, %

TT: n, %

C: n, %

T: n, %

Male

Hypertensive Patients

9, 24.3

18, 48.6

10, 27

36, 48.6

38, 51.4

0.028*

Healthy Controls

20, 62.5

10, 31.3

2, 6.3

50, 78.1

14, 21.9

12.7, 1, 0.0004

Female

Hypertensive Patients

19, 57.6

7, 21.2

7, 21.2

45, 68.2

21, 31.8

0.325*

Healthy Controls

20, 52.6

14, 36.8

4, 10.5

54, 71.1

22, 28.9

0.138, 1, 0.71

Total

Hypertensive Patients

28, 40

25, 35.7

17, 24.3

81, 57.9

59, 42.1

7.399, 1, 0.025

Healthy Controls

40, 57.1

24, 34.3

6, 8.6

104, 74.3

36, 25.7

8.428, 1, 0.004

  1. Statistically significant p values (> 0.05) were presented in bold for them to be distinguishable from the non-significant results
  2. *Fischer’s exact test