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Table 2 Genotype and allele frequencies for the MTHFR A1298C (rs1801131) polymorphism among groups

From: MTHFR C677T (rs1801133) genetic polymorphism is associated with development risk of essential hypertension in the Turkish population

 

Genotype

Allele

χ2, df, p

CC versus AA + AC

A versus C

AA: n, %

AC: n, %

CC: n, %

A: n, %

C: n, %

Male

Hypertensive Patients

10, 27

21, 56.8

6, 16.2

41, 55.4

33, 44.6

1*

Healthy Controls

11, 34.4

16, 50

5, 15.6

38, 59.4

26, 40.6

0.221, 1, 0.47

Female

Hypertensive Patients

19, 57.6

11, 33.3

3, 9.1

49, 74.2

17, 25.8

1*

Healthy Controls

15, 39.5

19, 50

4, 10.5

49, 64.5

27, 35.5

1.576, 1, 0.209

Total

Hypertensive Patients

29, 41.4

32, 45.7

9, 12.9

90, 64.3

50, 35.7

0, 1, 1

Healthy Controls

26, 37.1

35, 50

9, 12.9

87, 62.1

53, 37.9

0.138, 1, 0.71

  1. *Fischer’s exact test