Table 5 Comparison of both systolic and diastolic blood pressure values among genotype groups for the MTHFR C677T (rs1801133), MTHFR A1298C (rs1801131), FVL G1691A (rs6025) and PT G20210A (rs1799963) polymorphisms in hypertensive patients
Genetic polymorphism | Genotype | Systolic blood pressure | Diastolic blood pressure | p values |
|---|---|---|---|---|
Male | ||||
MTHFR C677T | CC | 147 ± 13.2 | 98 ± 10.4 | SBP: 0.253 DBP: 0.458 |
CT | 156 ± 11.3 | 102 ± 8.2 | ||
TT | 171 ± 10.5 | 105 ± 10.3 | ||
MTHFR A1298C | AA | 150 ± 10.1 | 96 ± 7.6 | SBP: 0.789 DBP: 0.869 |
AC | 152 ± 7.2 | 98 ± 4.8 | ||
CC | 154 ± 8.6 | 99 ± 10.8 | ||
FVL G1691A | GG | 151 ± 12.1 | 93 ± 8.4 | SBP: 0.756 DBP: 0.654 |
GA | 154 ± 8.4 | 95 ± 6.8 | ||
AA | 156 ± 10.2 | 98 ± 9.6 | ||
PT G20210A | GG | 149 ± 11.2 | 93 ± 8.2 | SBP: 0.648 DBP: 0.563 |
GA | 151 ± 8.9 | 95 ± 5.3 | ||
AA | 156 ± 7.5 | 97 ± 9.1 | ||
Female | ||||
MTHFR C677T | CC | 141 ± 8.8 | 92 ± 7.6 | SBP: 0.784 DBP: 0.987 |
CT | 150 ± 8.9 | 97 ± 5.6 | ||
TT | 165 ± 10.2 | 101 ± 7.4 | ||
MTHFR A1298C | AA | 146 ± 6.4 | 92 ± 5.7 | SBP: 0.986 DBP: 0.963 |
AC | 148 ± 7.2 | 93 ± 3.6 | ||
CC | 148 ± 8.6 | 95 ± 5.8 | ||
FVL G1691A | GG | 146 ± 8.4 | 91 ± 7.3 | SBP: 0.853 DBP: 0.954 |
GA | 148 ± 9.2 | 92 ± 7.8 | ||
AA | 151 ± 8.3 | 94 ± 8.6 | ||
PT G20210A | GG | 144 ± 7.4 | 91 ± 0.8 | SBP: 0.742 DBP:0.994 |
GA | 146 ± 8.6 | 92 ± 3.4 | ||
AA | 151 ± 7.6 | 94 ± 6.2 | ||
Total | ||||
MTHFR C677T | CC | 147 ± 13.2 | 98 ± 10.4 | SBP: 0.253 DBP: 0.458 |
CT | 156 ± 11.3 | 102 ± 8.2 | ||
TT | 171 ± 10.5 | 105 ± 10.3 | ||
MTHFR A1298C | AA | 150 ± 10.1 | 96 ± 7.6 | SBP: 0.789 DBP: 0.869 |
AC | 152 ± 7.2 | 98 ± 4.8 | ||
CC | 154 ± 8.6 | 99 ± 10.8 | ||
FVL G1691A | GG | 151 ± 12.1 | 93 ± 8.4 | SBP: 0.756 DBP: 0.654 |
GA | 154 ± 8.4 | 95 ± 6.8 | ||
AA | 156 ± 10.2 | 98 ± 9.6 | ||
PT G20210A | GG | 149 ± 11.2 | 93 ± 8.2 | SBP: 0.648 DBP: 0.563 |
GA | 151 ± 8.9 | 95 ± 5.3 | ||
AA | 156 ± 7.5 | 97 ± 9.1 | ||