Egyptian Journal of Medical Human Genetics

Table 1 High risk nsSNPs predicted by minimum six or more in silico programs

From: In-silico analysis unravels the structural and functional consequences of non-synonymous SNPs in the human IL-10 gene

SNP ID	Amino acid change	SIFT	PANTHER	PROVEAN	PhD-SNP	PMut	PolyPhen-2	SNPs&GO
rs1274280163	R42G	D	D	D	D	D	D	N
rs550164520	R45Q	D	D	D	D	D	D	D
rs745923816	F48L	D	D	D	D	D	D	N
rs545228684	E72G	D	D	D	D	D	D	N
rs1354773439	M95T	D	D	D	D	D	D	N
rs1421978042	A98D	D	D	D	D	D	D	D
rs771912629	R125S	D	D	D	D	D	D	N
rs1022828778	Y155C	D	D	D	D	D	D	D
rs1310781150	I168T	D	N	D	D	D	D	D

*Here, “D” indicates disease and “N” indicates neutral

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