Skip to main content

Table 2 Comparison between BRCA1 5382insC carriers and non-carriers

From: A case–control study of BRCA1 founder mutations 185delAG and 5382insC in a cohort of Egyptian ovarian cancer patients using pyrosequencing technique

Characteristic

FOC patients

FEp

Non-carrier (n = 46)

Carrier (n = 4)

No

%

No

%

Marital status

     

Not married

4

8.7

0

0.0

1.000

Married

42

91.3

4

100.0

 

State of menopause

     

Premenopausal

13

28.3

1

25.0

1.000

Menopausal

33

71.7

3

75.0

 

Parity

     

Nullipara

5

10.9

1

25.0

0.563

Unipara

3

6.5

0

0.0

 

Multipara

38

82.6

3

75.0

 

Affected family members

39

84.8

4

100

0.009*

One

35

76.1

1

25.0

 

Two

4

8.7

2

50.0

 

Three

0

0.0

1

25.0

 

Response to chemotherapy

     

Good

20

43.5

4

100.0

0.046*

No response

26

56.5

0

0.0

 

Survival

     

Died

1

2.2

0

0.0

1.000

Survived

45

97.8

4

100.0

 
  1. FE, Fisher’s exact test
  2. *Statistically significant at p ≤ 0.05