Impact of gene polymorphism of glutathione S-transferase and ghrelin as a risk factor in Egyptian women with gestational diabetes mellitus

Egyptian Journal of Medical Human Genetics

Table 4 Comparison of insulin resistance and lipid profile of gestational diabetes mellitus in pregnant women with healthy pregnant women

Parameters	GDM group (n = 70)	Control group (n = 70)	OR (95% CI)	P value
Insulin resistance Mean ± SD	24.20 ± 6.76	7.42 ± 2.66	undefined	˂ 0.001
Total lipids (mg/dL) Mean ± SD	1145.60 ± 171.20	605.32 ± 155.50	1.02 (1.01–1.03)	˂ 0.001
Total cholesterol (mg/dL) Mean ± SD	229.11 ± 34.78	150.03 ± 22.95	1.127 (1.09–1.17)	˂ 0.001
Triglycerides (mg/dL) Mean ± SD	299.25 ± 53.55	140.31 ± 32.26	5.25 (undefined)	˂ 0.001
LDL-cholesterol (mg/dL) Mean ± SD	142.0 ± 32.69	76.53 ± 18.05	1.16 (1.12–1.23)	˂ 0.001
VLDL-cholesterol (mg/dL) Mean ± SD	60.0 ± 11.45	29.06 ± 7.05	undefined	˂ 0.001
HDL-cholesterol (mg/dL) Mean ± SD	25.37 ± 6.09	51.45 ± 6.60	undefined	˂0.001

The data was presented as a mean and standard deviation
OR odds ratio, 95% CI 95% confidence interval for the difference between the means for both groups, GDM gestational diabetes mellitus. P is significant when ˂ 0.05