Table 1 SMA carrier results of 52 married couples (n = 106) and 10 obligate carries couples (n = 20) using real-time qPCR analysis
From: SMA carrier testing using Real-time PCR as a potential preconception screening tool
Subjects | Ratio of detected carriers | Range | Mean | SD | SE | CV% |
|---|---|---|---|---|---|---|
Both Parents Carriers (n = 66) | 57.4% | 0.326–0.93 | 0.65 | 0.15 | 0.019 | 23.41 |
One partner Carrier (n = 32) | 27.8% | 0.48–0.93 | 0.7 | 0.14 | 0.035 | 19.85 |
1.0–4.0 | 1.57 | 0.68 | 0.17 | 43.39 | ||
Both Parents Normal (n = 6) | 5.2% | 1.03 – 2.4 | 1.5 | 0.5 | 0.2 | 31.9 |
Obligate Carrier (n = 20) | 0% | 0.4–0.6 | 0.5 | 0.07 | 0.02 | 13.3 |