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Table 2 Frequency of promoter methylation in HCC and ANT n = 50

From: Significance of promoter methylation of multiple tumor suppressor genes in hepatocellular carcinoma

  

HCC, N (%)

ANT, N (%)

P, χ2

RASSF1A

M

40 (80)

12 (24)

0.046*

U

10 (20)

38 (76)

 

CHFR

M

35 (70)

19 (38)

0.018*

U

15 (30)

31 (62)

 

MGMT

M

28 (56)

10 (20)

0.001*

U

22 (44)

40 (80)

 

GSTP1

M

23 (46)

6 (12)

0.019*

U

27 (54)

44 (88)

 

hMLH1

M

7 (14)

5 (10)

0.001*

U

43 (86)

45 (90)

 
  1. HCC: hepatocellular carcinoma, ANT: adjacent non-tumorous tissue, U: unmethylation, P: partially methylation, M: methylation. *P value < 0.05 indicates statistical significance determined using the Pearson's χ2 test and Fisher’s exact test