Table 4 The genotype and allele distribution of rs17879961 and rs1042028 polymorphisms among cases and control
Cases (n = 86) | Control (n = 152) | χ2 | P | OR (95% C.I) | |
|---|---|---|---|---|---|
rs17879961 | |||||
TT (Thr/Thr)® | 28 (32.6%) | 63 (41.4%) | Ref | ||
TC (Thr/Ile) | 49 (57%) | 75 (49.3%) | 1.747 | 0.187 | 1.470 (0.829–2.606) |
CC (Ile/Ile) | 9 (10.5%) | 14 (9.2%) | 0.585 | 0.446 | 1.446 (0.560–3.734) |
Allele | |||||
T | 105 (61%) | 201 (66.1%) | 1.231 | 0.267 | Ref |
C | 67 (39%) | 103 (33.9%) | 1.245 (0.84–1.83) | ||
rs1042028 | |||||
CC (Arg/Arg) ® | 35 (40.7%) | 73 (48.0%) | Ref | ||
TC (Arg/His) | 45 (52.3%) | 63 (41.4%) | 1.985 | 0.160 | 1.490 (0.855–2.597) |
TT (His/His) | 6 (7.0%) | 16 (10.5%) | 0.223 | 0.637 | 0.782 (0.282–2.171) |
Allele | |||||
C | 115 (66.9%) | 209 (68.8%) | 0.180 | 0.671 | Ref |
T | 57 (33.1%) | 95 (31.3%) | 1.090(0.73–1.63) | ||