Table 7 Associations between rs17879961 and rs1042028 polymorphisms and clinicopathologic parameters of CRC
Cases (n = 86) | rs1042028 | χ2 | MCp | rs17879961 | χ2 | MCp | ||||
|---|---|---|---|---|---|---|---|---|---|---|
CC (n = 35) | TC (n = 45) | TT (n = 6) | TT (n = 28) | TC (n = 49) | CC (n = 9) | |||||
Site | ||||||||||
Rectum | 9 (25.7%) | 10 (22.2%) | 0 (0%) | 3.929 | 0.417 | 5 (17.9%) | 12 (24.5%) | 2 (22.2%) | 0.952 | 0.960 |
Colon | 26 (74.3%) | 32 (71.1%) | 6 (100%) | 22 (78.6%) | 35 (71.4%) | 7 (77.8%) | ||||
Rectosigmoid | 0 (0%) | 3 (6.7%) | 0 (0%) | 1 (3.6%) | 2 (4.1%) | 0 (0%) | ||||
Grade | ||||||||||
Low | 7 (20%) | 10 (22.2%) | 0 (0%) | 2.123 | 0.713 | 7 (25%) | 9 (18.4%) | 1 (11.1%) | 5.017 | 0.248 |
Intermediate | 25 (71.4%) | 29 (64.4%) | 5 (83.3%) | 16 (57.1%) | 37 (75.5%) | 6 (66.7%) | ||||
High | 3 (8.6%) | 6 (13.3%) | 1 (16.7%) | 5 (17.9%) | 3 (6.1%) | 2 (22.2%) | ||||
Dukes stage | ||||||||||
B | 1 (2.9%) | 0 (0%) | 0 (0%) | 3.244 | 0.777 | 1 (3.6%) | 0 (0%) | 0 (0%) | 3.682 | 0.480 |
C | 1 (2.9%) | 1 (2.2%) | 0 (0%) | 0 (0%) | 2 (4.1%) | 0 (0%) | ||||
D | 33 (94.3%) | 44 (97.8%) | 6 (100%) | 27 (96.4%) | 47 (95.9%) | 9 (100%) | ||||