Skip to main content

Table 7 Associations between rs17879961 and rs1042028 polymorphisms and clinicopathologic parameters of CRC

From: Association of CHEK2 I157T and SULT1A1 R213H genetic variants with risk of sporadic colorectal cancer in a sample of Egyptian patients

Cases (n = 86) rs1042028 χ2 MCp rs17879961 χ2 MCp
CC (n = 35) TC (n = 45) TT (n = 6) TT (n = 28) TC (n = 49) CC (n = 9)
Site
Rectum 9 (25.7%) 10 (22.2%) 0 (0%) 3.929 0.417 5 (17.9%) 12 (24.5%) 2 (22.2%) 0.952 0.960
Colon 26 (74.3%) 32 (71.1%) 6 (100%)    22 (78.6%) 35 (71.4%) 7 (77.8%)   
Rectosigmoid 0 (0%) 3 (6.7%) 0 (0%)    1 (3.6%) 2 (4.1%) 0 (0%)   
Grade
Low 7 (20%) 10 (22.2%) 0 (0%) 2.123 0.713 7 (25%) 9 (18.4%) 1 (11.1%) 5.017 0.248
Intermediate 25 (71.4%) 29 (64.4%) 5 (83.3%)    16 (57.1%) 37 (75.5%) 6 (66.7%)   
High 3 (8.6%) 6 (13.3%) 1 (16.7%)    5 (17.9%) 3 (6.1%) 2 (22.2%)   
Dukes stage
B 1 (2.9%) 0 (0%) 0 (0%) 3.244 0.777 1 (3.6%) 0 (0%) 0 (0%) 3.682 0.480
C 1 (2.9%) 1 (2.2%) 0 (0%)    0 (0%) 2 (4.1%) 0 (0%)   
D 33 (94.3%) 44 (97.8%) 6 (100%)    27 (96.4%) 47 (95.9%) 9 (100%)   
  1. χ2 chi-square test, MC Monte Carlo test
  2. p: p value for comparing between the different categories