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Table 4 Relation between IL28 B genotype and ALT / and viral load by PCR for the all studied patients

From: Impact of IL-28B gene polymorphism on chronic hepatitis-C patients progression with diabetes and non-diabetes

Parameter CC
(n = 40)
CT
(n = 82)
TT
(n = 38)
K p
ALT(U/L)
Mean ± SD
Median
Range
37.35 ± 26.02
30
10–143
54.49 ± 27.21
50.5
14–161
71.58 ± 33.83
63
15–175
34.39  < 0.001***
PCR (IU/mL)
Mean ± SD
Median
Range
153,050 ± 399,946
31,000
1600–1,800,000
1,081,300 ± 2,754,340
90,000
1200–16,200,000
578,060 ± 1,454,550
380,000
3200–7,500,000
11.45 0.003*
  1. ALT: alanine aminotransferase PCR: polymerase chain reaction SD: standard deviation K = Kruskal–Wallis test ***: highly significant
  2. Least significant difference (LSD) of ALT between genotypes: (CC versus CT p = 0.002 CC versus TT p =  < 0.001. CT versus TT p = 0.004). LSD of PCR between genotypes: (CC versus CT p = 0.034. CC versus TT p = 0.009. CT versus TT p = 0.01)