Impact of IL-28B gene polymorphism on chronic hepatitis-C patients progression with diabetes and non-diabetes

Egyptian Journal of Medical Human Genetics

Table 5 Multivariate logistic regression analysis for significant predictors of CHC disease progression

Variable	B	S.E	OR	95.0% C.I		χ²	p	Rank
Variable	B	S.E	OR	Lower	Upper	χ²	p	Rank
Age > 48	1.27	0.42	2.76	1.76	5.34	6.74	0.04**	6
BMI > 25	0.81	0.43	0.79	0.354	1.791	0.53	0.61*	7
T2DM	2.98	0.45	4.28	2.31	10.94	6.89	0.03**	4
Genotype CC versus CT	2.11	0.49	4.35	2.56	11.55	8.09	0.02**	3
Genotype CC versus TT	1.82	0.56	3.45	2.12	7.14	7.12	0.04**	5
ALT > 45 U/L	3.12	0.54	9.56	4.56	16.34	11.22	< 0.001***	2
Viral load > 1,000,000 IU/ml	4.1	0.62	11.27	5.63	29.45	12.03	< 0.001***	1

B = coefficient of regression, S. E = standard error, OR: odds ratio, CI: confidence interval, X² = Chi-square test, *nonsignificant p > 0.05 **significant p < 0.05 ***highly significant p < 0.001