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Table 2 Genotypic and allelic frequencies of rs3746444 A > G and rs2910164 C > G in the studied groups

From: Pre-microRNAs single nucleotide variants (rs3746444 A > G and rs2910164 C > G) increase the risk of ischemic stroke in the Egyptian population: a case–control study

Parameters

Control (n.100)

No (%)

Cases (n.100)

No (%)

p Value*

OR

95% CI

rs3746444 A > G

Genotypes

GG

18 (18)

48 (48)

 < 0.001*

3.930

1.990–7.761

AG

26 (26)

14 (14)

0.556

0.794

0.368–1.713

GG + AG

44 (44)

62 (62)

0.011*

2.077

1.181–3.653

AA

56 (56)

38 (38)

Reference

PHWE

 < 0.001

 < 0.001

 

Alleles

G

62 (31)

110 (55)

 < 0.001*

2.720

1.807–4.096

A

138 (69)

90 (45)

Reference

rs2910164 C > G

Genotypes

GG

31 (31)

39 (39)

0.057

2.053

0.979–4.305

GC

38 (38)

42 (42)

0.109

1.803

0.878–3.705

GG + GC

69 (69)

81 (81)

0.052

1.915

0.995–3.688

CC

31 (31)

19 (19)

Reference

PHWE

0.0164

0.2113

 

Alleles

G

100 (50)

120 (60)

0.045*

1.500

1.009–2.229

C

100 (50)

80 (40)

Reference

  1. HWE Hardy–Weinberg equilibrium
  2. *p Value ≤ 0.05 is statistically significant