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Table 2 Genotypic and allelic frequencies of rs3746444 A > G and rs2910164 C > G in the studied groups

From: Pre-microRNAs single nucleotide variants (rs3746444 A > G and rs2910164 C > G) increase the risk of ischemic stroke in the Egyptian population: a case–control study

Parameters Control (n.100)
No (%)
Cases (n.100)
No (%)
p Value* OR 95% CI
rs3746444 A > G
Genotypes
GG 18 (18) 48 (48)  < 0.001* 3.930 1.990–7.761
AG 26 (26) 14 (14) 0.556 0.794 0.368–1.713
GG + AG 44 (44) 62 (62) 0.011* 2.077 1.181–3.653
AA 56 (56) 38 (38) Reference
PHWE  < 0.001  < 0.001  
Alleles
G 62 (31) 110 (55)  < 0.001* 2.720 1.807–4.096
A 138 (69) 90 (45) Reference
rs2910164 C > G
Genotypes
GG 31 (31) 39 (39) 0.057 2.053 0.979–4.305
GC 38 (38) 42 (42) 0.109 1.803 0.878–3.705
GG + GC 69 (69) 81 (81) 0.052 1.915 0.995–3.688
CC 31 (31) 19 (19) Reference
PHWE 0.0164 0.2113  
Alleles
G 100 (50) 120 (60) 0.045* 1.500 1.009–2.229
C 100 (50) 80 (40) Reference
  1. HWE Hardy–Weinberg equilibrium
  2. *p Value ≤ 0.05 is statistically significant