Table 4 Relations of rs3746444 A > G genotypic frequencies to clinical data
Parameters | rs3746444 A > G | rs3746444 A > G | |||||
|---|---|---|---|---|---|---|---|
GG N (%) | AG N (%) | AA N (%) | p Value* | GG + AG N (%) | AA N (%) | p Value* | |
Age (years) | |||||||
≤ 40 Years | 4 (8.3) | 3 (21.4) | 4 (10.5) | 0.382 | 7 (11.3) | 4 (10.5) | 1 |
> 40 Years | 44 (91.7) | 11 (78.6) | 34 (89.5) | 55 (88.7) | 34 (89.5) | ||
Mean ± SD | 56.50 ± 10.86 | 51.43 ± 10.99 | 54.47 ± 10.90 | 0.272 | 55.35 ± 11.01 | 54.47 ± 10.90 | 0.541 |
Gender | |||||||
Males | 31 (64.6) | 11 (78.6) | 23 (60.5) | 0.528 | 42 (67.7) | 23 (60.5) | 0.463 |
Females | 17 (35.4) | 3 (21.4) | 15 (39.5) | 20 (32.3) | 15 (39.5) | ||
Risk factors of stroke | |||||||
Smoker | 20 (41.7) | 6 (42.9) | 15 (39.5) | 0.968 | 26 (41.9) | 15 (39.5) | 0.808 |
DM | 25 (52.1) | 4 (28.6) | 20 (52.6) | 0.257 | 29 (46.8) | 20 (52.6) | 0.570 |
HTN | 35 (72.9) | 5 (35.7) | 21 (55.3) | 0.028* | 40 (64.5) | 21 (55.3) | 0.357 |
Hyperlipidemia | 12 (25) | 5 (35.7) | 13 (34.2) | 0.626 | 17 (27.4) | 13 (34.2) | 0.472 |
NIHH score | |||||||
Mild | 25 (52.1) | 7 (50) | 17 (44.7) | 0.729 | 32 (51.6) | 17 (44.7) | 0.338 |
Moderate | 21 (43.8) | 7 (50) | 17 (44.7) | 28 (45.2) | 17 (44.7) | ||
Severe | 7 (4.2) | 0 (0) | 4 (10.5) | 2 (3.2) | 4 (10.5) | ||
Duplex atherosclerotic scoring | |||||||
Normal | 7 (14.6) | 5 (35.7) | 9 (23.7) | 0.335 | 12 (19.4) | 9 (23.7) | 0.614 |
Mild | 25 (52.1) | 4 (28.6) | 15 (39.5) | 29 (46.8) | 15 (39.5) | ||
Moderate | 11 (22.9) | 2 (14.3) | 6 (15.8) | 13 (21) | 6 (15.8) | ||
Severe | 5 (10.4) | 3 (21.4) | 8 (21.1) | 8 (12.9) | 8 (21.1) | ||
CRP levels | |||||||
Normal ≤ 5 mg/L | 6 (12.5) | 3 (21.4) | 23 (60.5) | < 0.001* | 9 (14.5) | 23 (60.5) | < 0.001* |
Abnormal > 5 mg/L | 42 (87.5) | 11 (78.6) | 15 (39.5) | 53 (85.5) | 15 (39.5) | ||
Mean ± SD | 26.60 ± 18.54 | 20.39 ± 20.11 | 8.34 ± 10.81 | < 0.001* | 25.20 ± 18.92 | 8.34 ± 10.81 | < 0.001* |