Skip to main content

Table 5 Relations of rs2910164 C > G genotypic frequencies to clinical data

From: Pre-microRNAs single nucleotide variants (rs3746444 A > G and rs2910164 C > G) increase the risk of ischemic stroke in the Egyptian population: a case–control study

Parameters rs2910164 C > G rs2910164 C > G
GG
N (%)
GC
N (%)
CC
N (%)
p Value* GG + GC
N (%)
CC
N (%)
p Value*
Age (years)
 < 40 Years 6 (15.4) 4 (9.5) 1 (5.3) 0.540 10 (12.3) 1 (5.3) 0.685
 > 40 Years 33 (84.6) 38 (90.5) 18 (94.7) 87.7 (87.7) 18 (94.7)
Mean ± SD 55.51 ± 11.58 53.71 ± 10.62 56.89 ± 10.38 0.407 54.58 ± 11.06 56.89 ± 10.38 0.426
Gender
Males 22 (56.4) 30 (71.4) 13 (68.4) 0.345 52 (64.2) 13 (68.4) 0.728
Females 17 (43.6) 12 (28.6) 6 (31.6) 29 (35.8) 6 (31.6)
Risk factors of stroke
Smoker 15 (38.5) 20 (47.6) 6 (31.6) 0.458 35 (43.2) 6 (31.6) 0.354
DM 18 (46.2) 25 (59.5) 6 (31.6) 0.117 43 (53.1) 6 (31.6) 0.091
HTN 25 (64.1) 24 (57.1) 12 (63.2) 0.795 49 (60.5) 12 (63.2) 0.830
Hyperlipidemia 13 (33.3) 12 (28.6) 5 (26.3) 0.831 25 (30.9) 5 (26.3) 0.697
NIHH score
Mild 21 (53.8) 21 (50) 7 (36.8) 0.732 42 (51.9) 7 (36.8) 0.282
Moderate 16 (41) 19 (45.2) 10 (52.6) 35 (43.2) 10 (52.6)
Severe 2 (5.1) 2 (4.8) 2 (10.5) 4 (4.9) 2 (10.5)
Duplex atherosclerotic scoring
Normal 7 (17.9) 10 (23.8) 4 (21.1) 0.987 17 (21) 4 (21.1) 0.950
Mild 17 (43.6) 18 (42.9) 9 (47.4) 35 (43.2) 9 (47.4)
Moderate 8 (20.5) 7 (16.7) 4 (21.1) 15 (18.5) 4 (21.1)
Severe 7 (17.9) 7 (16.7) 2 (10.5) 14 (17.3) 2 (10.5)
CRP levels
Normal ≤ 5 mg/L 11 (28.2) 15 (35.7) 6 (31.6) 0.769 26 (32.1) 6 (31.6) 0.965
Abnormal > 5 mg/L 28 (71.8) 27 (64.3) 13 (68.4) 55 (67.9) 13 (68.4)
Mean ± SD 17.34 ± 16.61 18.90 ± 19.90 21.54 ± 18.11 0.731 18.15 ± 18.29 21.54 ± 18.11 0.431
  1. DM Diabetes Mellitus, HTN hypertension, SD standard deviation, NIHSS National Institutes of Health Stroke Scale
  2. *p Value ≤ 0.05 is statistically significant