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Table 5 Relations of rs2910164 C > G genotypic frequencies to clinical data

From: Pre-microRNAs single nucleotide variants (rs3746444 A > G and rs2910164 C > G) increase the risk of ischemic stroke in the Egyptian population: a case–control study

Parameters

rs2910164 C > G

rs2910164 C > G

GG

N (%)

GC

N (%)

CC

N (%)

p Value*

GG + GC

N (%)

CC

N (%)

p Value*

Age (years)

 < 40 Years

6 (15.4)

4 (9.5)

1 (5.3)

0.540

10 (12.3)

1 (5.3)

0.685

 > 40 Years

33 (84.6)

38 (90.5)

18 (94.7)

87.7 (87.7)

18 (94.7)

Mean ± SD

55.51 ± 11.58

53.71 ± 10.62

56.89 ± 10.38

0.407

54.58 ± 11.06

56.89 ± 10.38

0.426

Gender

Males

22 (56.4)

30 (71.4)

13 (68.4)

0.345

52 (64.2)

13 (68.4)

0.728

Females

17 (43.6)

12 (28.6)

6 (31.6)

29 (35.8)

6 (31.6)

Risk factors of stroke

Smoker

15 (38.5)

20 (47.6)

6 (31.6)

0.458

35 (43.2)

6 (31.6)

0.354

DM

18 (46.2)

25 (59.5)

6 (31.6)

0.117

43 (53.1)

6 (31.6)

0.091

HTN

25 (64.1)

24 (57.1)

12 (63.2)

0.795

49 (60.5)

12 (63.2)

0.830

Hyperlipidemia

13 (33.3)

12 (28.6)

5 (26.3)

0.831

25 (30.9)

5 (26.3)

0.697

NIHH score

Mild

21 (53.8)

21 (50)

7 (36.8)

0.732

42 (51.9)

7 (36.8)

0.282

Moderate

16 (41)

19 (45.2)

10 (52.6)

35 (43.2)

10 (52.6)

Severe

2 (5.1)

2 (4.8)

2 (10.5)

4 (4.9)

2 (10.5)

Duplex atherosclerotic scoring

Normal

7 (17.9)

10 (23.8)

4 (21.1)

0.987

17 (21)

4 (21.1)

0.950

Mild

17 (43.6)

18 (42.9)

9 (47.4)

35 (43.2)

9 (47.4)

Moderate

8 (20.5)

7 (16.7)

4 (21.1)

15 (18.5)

4 (21.1)

Severe

7 (17.9)

7 (16.7)

2 (10.5)

14 (17.3)

2 (10.5)

CRP levels

Normal ≤ 5 mg/L

11 (28.2)

15 (35.7)

6 (31.6)

0.769

26 (32.1)

6 (31.6)

0.965

Abnormal > 5 mg/L

28 (71.8)

27 (64.3)

13 (68.4)

55 (67.9)

13 (68.4)

Mean ± SD

17.34 ± 16.61

18.90 ± 19.90

21.54 ± 18.11

0.731

18.15 ± 18.29

21.54 ± 18.11

0.431

  1. DM Diabetes Mellitus, HTN hypertension, SD standard deviation, NIHSS National Institutes of Health Stroke Scale
  2. *p Value ≤ 0.05 is statistically significant