A study of nasal epithelial cell gene expression in a sample of mild to severe asthmatic children and healthy controls

Egyptian Journal of Medical Human Genetics

Table 2 Global subject characteristics

Variables	Control group (N = 30)	Mild persistent (N = 34)	Moderate persistent (N = 26)	Severe persistent (N = 10)	ANOVA	P
Variables	Mean ± SD	Mean ± SD	Mean ± SD	Mean ± SD	ANOVA	P
Age (years)	10.7 ± 3.3	10.4 ± 3.2	11 ± 3.2	9.8 ± 2.4	0.417	0.741
Sex
Male N (%)	15 (50%)	20 (58.8%)	10 (38.5%)	6 (60%)	χ² = 2.8	0.419
Female N (%)	15 (50%)	14 (41.2%)	16 (61.5%)	4 (40%)
Eosinophils cells × 10⁹/L	213.5 ± 54.4	251.6 ± 87.0	412.4 ± 34.1	549.8 ± 44.2	96.6	< 0.001*
Serum IgE IU\mL	156.3 ± 34.6	482.8 ± 120.3	733.8 ± 147.8	1019.4 ± 137.0	119.4	< 0.001*
FEV1\ FVC	89.4 ± 1.44	87.5 ± 4.02	78.4 ± 2.89	65. 3 ± 7.75	184.4	< 0.001*
FEV1%	95.05 ± 2.09	84.4 ± 1.56	70.2 ± 4.14	52.0 ± 6.51	352.9	< 0.001*
FVC%	92.7 ± 2.51	88.0 ± 4.75	72.3 ± 5.00	55.5 ± 7.20	43.1	< 0.001*

FVC: forced vital capacity, FEV1: forced expiratory volume in 1st second, IgE: Immunoglobulin E
*P < 0.05 is significant