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Table 3 Expression of nasal epithelial cell genes in the studied groups

From: A study of nasal epithelial cell gene expression in a sample of mild to severe asthmatic children and healthy controls

Variables Control group
(N = 30)
Mild persistent
(N = 34)
Moderate persistent (N = 26) Severe persistent
(N = 10)
Kruskal–Wallis test (χ2) P
Mean ± SE Mean ± SE Mean ± SE Mean ± SE
TMEM178 6.251 ± 0.149 4.703 ± 0.12
(0.75 fold)
3.521 ± 0.181
(0.56 fold)
1.293 ± 0.295
(0.2 fold)
77.59 p1 = 0.001* p2 = 0.001*
p3 = 0.001* p4 = 0.001*
p5 = 0.001* p6 = 0.001*
FKBP5 0.47 ± 0.049 0.496 ± 0.047
(1.055 fold)
0.608 ± 0.059
(1.29 fold)
0.64 ± 0.087
(1.36 fold)
5.38 p1 = 0.747 p2 = 0.063
p3 = 0.104 p4 = 0.121
p5 = 0.17; p6 = 0.89
CLCA1 0.026 ± 0.006 0.047 ± 0.005
(1.81 fold)
0.049 ± 0.006
(1.88 fold)
0.064 ± 0.014
(2.46 fold)
13.58 p1 = 0.002* p2 = 0.003*
p3 = 0.046* p4 = 0.77
p5 = 0.28; p6 = 0.34
SERPINB2 0.067 ± 0.01 2.01 ± 0.13
(30 fold)
2.33 ± 0.22
(34.78 fold)
2.66 ± 0.28
(39.7 fold)
63.86 p1 = 0.001* p2 = 0.001*
p3 = 0.001* p4 = 0.45
p5 = 0.06; p6 = 0.42
Periostin 0.022 ± 0.005 0.061 ± 0.016
(2.77 fold)
0.115 ± 0.039
(5.23 fold)
0.097 ± 0.038
(4.41 fold)
19.3 p1 = 0.001*; p2 = 0.001*
p3 = 0.006*; p4 = 0.17
p5 = 34; p6 = 0.97
  1. p1: mild and control, p2: moderate and control, p3: severe and control, p4: mild and moderate, p5: mild and severe, p6: moderate and severe, TMEM178: transmembrane protein 178, CLCA1: chloride pathway, calcium activated family member 1, SERPINB2: serpin peptidase inhibitor, clade B, member 2
  2. *P < 0.05 is significant