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Table 5 Performance characteristics of FKBP51, CLCA1, SERPINB2 and periostin expression (2−∆Ct) to detect asthma

From: A study of nasal epithelial cell gene expression in a sample of mild to severe asthmatic children and healthy controls

Variables AUC (95% CI) Cutoff points Sensitivity (%) Specificity (%) P value
FKBP51 0.410 (0.291–0.529) 0.566 43.3 50 > 0.05
CLCA1 0.272 (0.150–0.393) 0.0747 20 70 < 0.001*
SERPINB2 0.083 (0.052–0.141) 1.220 20 20 < 0.001*
Periostin 0. 234 (0.127–0.342) 0.0314 26.7 60 < 0.001*
  1. CI: confidence interval, CLCA1: chloride pathway, calcium activated family member 1, SERPINB2: serpin peptidase inhibitor, clade B, member 2
  2. *P < 0.05 is significant