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Egyptian Journal of Medical Human Genetics

Table 7 Performance characteristics of TMEM178, FKBP51, CLCA1, SERPINB2 and periostin expression (2−∆Ct) to detect atopic status

From: A study of nasal epithelial cell gene expression in a sample of mild to severe asthmatic children and healthy controls

Variables

AUC (95% CI)

Cutoff points

Sensitivity (%)

Specificity (%)

P value

TMEM178

0.622 (0.490–0.754)

4.273

50

63.2

0.081

FKBP51

0.481 (0.340–0.622)

0.573

50

50

0.786

CLCA1

0.701 (0.579–0.824)

0.063

53.1

81.6

0.004*

SERPINB2

0.919 (0.852–0.987)

2.325

84.4

92.1

 < 0.001*

Periostin

0. 842 (0.742–0.941)

0.041

81.3

84.2

 < 0.001*

  1. CI: confidence interval, TMEM178: transmembrane protein 178, CLCA1: chloride pathway, calcium activated family member 1, SERPINB2: serpin peptidase inhibitor, clade B, member 2
  2. *P < 0.05 is significant
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