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Table 1 Characteristics of patients and controls

From: Association of Keap1 (rs11085735) polymorphism and lncRNA MEG3 hypermethylation status with the risk of preeclampsia

Variables

All patients

n = 75

Severe preeclampsia

n = 28

Mild preeclampsia

N = 47

Controls

n = 75

Age, year

31.5 ± 6.6; p = 0.018

29.6 ± 6.9; p = 0.8

32.6 ± 6.2; p = 0.008

29 ± 6.1

Gestational age, weeks

35.3 ± 2.2; p < 0.001

35.2 ± 2.1; p < 0.001

35.4 ± 2.4; p < 0.001

37.5 ± 2.1

Weight(before pregnancy), kg

71.2 ± 10.7; p = 0.09

70.9 ± 13.4; p = 0.5

71.5 ± 9.1; p = 0.26

68 ± 12

Weight ( after pregnancy), kg

81.3 ± 12.7; p = 0.4

80.3 ± 14.4; p = 0.9

81.9 ± 11.8; p = 0.66

79.7 ± 12.7

BMI ( before pregnancy), kg/m2

26.3 ± 6.2; p = 0.008

25.9 ± 7.5; p = 0.1

26.6 ± 5.4; p = 0.037

22.8 ± 9.2

BMI ( after pregnancy), kg/m2

30.2 ± 7.2; p = 0.004

29.9 ± 8.4; p = 0.1

30.4 ± 6.6; p = 0.024

25.4 ± 11.9

Systolic blood pressure, mm Hg

152 ± 16.3; p < 0.001

165 ± 17.5; p < 0.001

144.4 ± 9.4; p < 0.001

113.3 ± 7.5

Diastolic blood pressure, mm Hg

93.3 ± 15.2; p < 0.001

102.6 ± 11.9; p < 0.001

87.8 ± 14.3; p < 0.001

73.5 ± 5.4

Platelet count × 103/μL

152.7 ± 36.3; p = 0.026

152.2 ± 33.6; p = 0.02

153.1 ± 38.1; p = 0.015

187.2 ± 47.8

Urea, mg/dL

26.2 ± 7.3; p < 0.001

26.8 ± 7.4; p < 0.001

25.8 ± 7.3; p = 0.001

19.6 ± 6.5

Creatinine, mg/dL

0.7 ± 0.2; p = 0.3

0.8 ± 0.2; p = 0.5

0.75 ± 0.2; p = 0.38

1.4 ± 3.8

AST, U/L

39.2 ± 45.5; p = 0.001

38.3 ± 47.3; p = 0.1

39.7 ± 45; p = 0.046

19.9 ± 7.1

ALT, U/L

28.5 ± 27.5; p < 0.001

28.7 ± 25; p = 0.05

28.5 ± 29; p = 0.028

15.3 ± 8

ALP, U/L

350.5 ± 131; p = 0.006

352.6 ± 132.8; p = 0.05

349.3 ± 131.4; p = 0.036

280.1 ± 108.2

Direct bilirubin, mg/dL

0.31 ± 0.13; p = 0.2

0.2 ± 0.08; p = 0.9

0.33 ± 0.16; p = 0.21

0.2 ± 0.1

Total bilirubin, mg/dL

0.76 ± 0.29; p = 0.001

0.6 ± 0.2; p = 0.03

0.77 ± 0.3; p = 0.0.006

0.57 ± 0.26