Table 7 Correlation of progression free survival with other variables
From: Interleukin-4 gene intron 3 VNTR polymorphism in adult acute myeloid leukemia
Total N | N of events | PFS (months) | 95% CI | Survival at | Log Rank test | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Mean | SE | Lower | Upper | 1 m. (%) | 3 m. (%) | 6 m. (%) | 12 m. (%) | X2 | P value | Sig | ||||
Overall | 40 | 8 | 18.31 | 1.68 | 15.03 | 21.60 | 100.0 | 93.8 | 78.1 | 65.1 | – | – | – | |
Age | ≤ 45 yrs | 22 | 3 | 20.14 | 1.97 | 16.27 | 24.01 | 100.0 | 100.0 | 78.6 | 78.6 | 0.997 | 0.318 | NS |
> 45 yrs | 18 | 5 | 16.65 | 2.51 | 11.72 | 21.58 | 100.0 | 87.5 | 78.8 | 52.5 | ||||
Sex | Females | 24 | 3 | 10.41 | 0.83 | 8.79 | 12.03 | 100.0 | 88.2 | 79.4 | 79.4 | 0.090 | 0.764 | NS |
Males | 16 | 5 | 17.79 | 2.19 | 13.50 | 22.08 | 100.0 | 100.0 | 78.6 | 58.9 | ||||
TLC | TLC < 20 | 21 | 4 | 18.49 | 2.22 | 14.13 | 22.85 | 100.0 | 100.0 | 85.7 | 61.2 | 0.179 | 0.672 | NS |
TLC ≥ 20 | 19 | 4 | 18.08 | 2.50 | 13.19 | 22.97 | 100.0 | 86.7 | 69.3 | 69.3 | ||||
HGB | < 7.5 | 21 | 4 | 18.57 | 2.27 | 14.13 | 23.01 | 100.0 | 100.0 | 78.6 | 65.5 | 0.062 | 0.803 | NS |
> 7.5 | 19 | 4 | 18.23 | 2.43 | 13.46 | 22.99 | 100.0 | 87.5 | 78.8 | 65.6 | ||||
PLT | < 40 | 21 | 4 | 17.71 | 2.57 | 12.68 | 22.74 | 100.0 | 93.3 | 76.4 | 61.1 | 0.088 | 0.767 | NS |
≥ 40 | 19 | 4 | 18.79 | 2.21 | 14.47 | 23.12 | 100.0 | 94.1 | 79.6 | 68.3 | ||||
PB blasts | < 32 | 19 | 5 | 16.69 | 2.47 | 11.85 | 21.53 | 100.0 | 93.3 | 77.8 | 51.9 | 0.625 | 0.429 | NS |
> 32 | 21 | 3 | 19.94 | 2.09 | 15.84 | 24.04 | 100.0 | 94.1 | 78.4 | 78.4 | ||||
Initial aspirate | < 69 | 20 | 3 | 19.20 | 2.40 | 14.51 | 23.89 | 100.0 | 100.0 | 84.6 | 67.7 | 0.492 | 0.483 | NS |
> 69 | 20 | 5 | 17.40 | 2.39 | 12.71 | 22.10 | 100.0 | 88.2 | 72.2 | 61.9 | ||||
Extramedullary involvement | Negative | 25 | 7 | 16.78 | 2.10 | 12.67 | 20.88 | 100.0 | 95.0 | 71.2 | 55.4 | 1.599 | 0.206 | NS |
Positive | 15 | 1 | 22.25 | 1.68 | 18.97 | 25.53 | 100.0 | 91.7 | 91.7 | 91.7 | ||||
Diagnosis | M0 | 1 | 0 | – | – | – | – | 100.0 | 100.0 | 100.0 | 100.0 | 0.139 | 0.933 | NS |
M1 | 7 | 0 | – | – | – | – | 100.0 | 100.0 | 100.0 | 100.0 | ||||
M2 | 20 | 5 | 17.59 | 2.35 | 12.99 | 22.20 | 100.0 | 88.2 | 74.7 | 62.2 | ||||
M3 | 3 | 1 | 20.00 | 3.27 | 13.60 | 26.40 | 100.0 | 100.0 | 100.0 | 66.7 | ||||
M4 | 8 | 2 | 16.80 | 3.94 | 9.07 | 24.53 | 100.0 | 100.0 | 60.0 | 60.0 | ||||
M7 | 1 | 0 | – | – | – | – | 100.0 | 100.0 | 100.0 | 100.0 | ||||
HLA-DR | Negative | 7 | 1 | 21.00 | 2.60 | 15.91 | 26.09 | 100.0 | 100.0 | 100.0 | 75.0 | 0.602 | 0.438 | NS |
Positive | 33 | 7 | 17.79 | 1.94 | 13.99 | 21.60 | 100.0 | 92.3 | 72.9 | 63.8 | ||||
CD34 | Negative | 10 | 1 | 21.60 | 2.15 | 17.39 | 25.81 | 100.0 | 100.0 | 100.0 | 80.0 | 1.477 | 0.224 | NS |
Positive | 30 | 7 | 17.17 | 2.09 | 13.08 | 21.26 | 100.0 | 91.7 | 70.1 | 60.1 | ||||
PCR product | P1P1 | 1 | 0 | – | – | – | – | 100.0 | 100.0 | 100.0 | 100.0 | 0.482 | 0.786 | NS |
P2P2 | 22 | 5 | 18.06 | 2.15 | 13.85 | 22.27 | 100.0 | 94.1 | 81.6 | 61.2 | ||||
P1P2 | 17 | 3 | 18.32 | 2.80 | 12.83 | 23.81 | 100.0 | 92.9 | 69.6 | 69.6 | ||||