Study of the association between GLIS3 rs10758593 and type 2 diabetes mellitus in Egyptian population

Egyptian Journal of Medical Human Genetics

Table 3 Descriptive and comparative statistics of routine laboratory tests between different genotypes among T2DM patients using Wilcoxon rank sum test

	Patients (T2DM) (n = 100)
	AA (n = 39)	AG (n = 61)	z value	p value	Sig.
Age (years) Median (IQR)	53 (46–58)	51 (46–58)	− 0.134	0.893	NS
BMI Median (IQR)	29 (27.1–31)	29 (27–31)	− 0.361	0.718	NS
HbA1C (%) Median (IQR)	9.1 (7.4–10.6)	7.7 (7.0–8.8)	− 2.588	0.01	S
Fasting blood glucose (mg/dL) Median (IQR)	223 (168–29 8)	175 (130–217)	− 3.032	0.002	S
Fasting insulin(mIU/L) Median (IQR)	18 (16–24)	13 (11–17)	− 4.641	< 0.001	HS
HOMA-IR Median (IQR)	10.49 (8.69–13.14)	5.84 (4.16–7.95)	− 5.307	< 0.001	HS

IQR interquartile range, p value probability, BMI body mass index, T2DM type 2 diabetes mellitus, HbA1C glycated hemoglobin, HOMA-IR homeostatic model assessment for insulin resistance, n number, NS non-significant, S Significant, HS highly significant