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Table 4 Prediction of diagnostic value by selected biomarkers (log2 fold change)

From: Expression and diagnostic values of MIAT, H19, and NRON long non-coding RNAs in multiple sclerosis patients

Parameter

AUC ± SE

95% CI

P

Se (%)

Sp (%)

Diagnostic value

Expression MIAT

0.861 ± 0.029

0.804–0.918

 < 0.0001

89.47

80.00

Expression H19

0.941 ± 0.019

0.903–0.979

 < 0.0001

91.58

91.58

Expression NRON

0.951 ± 0.015

0.922–0.981

 < 0.0001

93.68

91.58

Combination of all genes

0.966 ± 0.016

0.935–0.997

 < 0.0001

93.68

98.95

  1. Abbreviations: AUC, area under the curve; CI, confidence interval; Se, sensitivity; Sp, specificity
  2. The diagnostic analyses were conducted after combining with age and sex, using multiple logistic regression. P < 0.05 was considered statistically significant