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Egyptian Journal of Medical Human Genetics

Table 2 Observed and expected values of FTO rs9939609 (T>A) and FTO rs1421085 (T>C) variants in PCOS patients and controls by Hardy–Weinberg equilibrium

From: Association of FTO gene variants rs9939609 and rs1421085 with polycystic ovary syndrome

Gene polymorphism

Control

PCOS

O

E

χ2

p

O

E

χ2

p

FTO

rs9939609

TT

29

32.2

1.77P

0.00A

0.183P

> 0.999A

47

45.1

0.75P

0.00A

0.385P

> 0.999A

TA

55

48.5

  

39

42.8

  

AA

15

18.2

  

12

10.1

  

FTO

rs1421085

TT

32

25.8

6.30P

0.00A

0.012P*

0.998A

28

27.6

0.03P

0.00A

0.869P

0.995A

TC

37

49.5

  

48

48.8

  

CC

30

23.8

  

22

21.6

  
  1. PCOS: polycystic ovarian syndrome; O: observed data; E: expected data; P: Pearson Chi-Square (χ2) test; A: Chi-Square (χ2) test for trend (Armitage trend test); p: significance value
  2. *Significant difference. p < 0.05 was considered statistically significant
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