Genotypes | GDM (n = 160) | Control (n = 165) | X2 values | P values | Risk /OR (95% CI) |
---|---|---|---|---|---|
ACE (I/D) | |||||
II | 8 (5%) | 80 (48.5%) | |||
ID | 68 (42.5%) | 50 (30.3%) | |||
DD | 84 (52.5%) | 35 (21.2%) | 81.77 | 0.000* | |
II | 8 (5%) | 80 (48.5%) | |||
ID + DD | 152 (95%) | 85 (51.5%) | 77.8 | 0.000* | 17.88 (8.25–38.77) |
ID + II | 76 (47.5%) | 130 (78.8%) | |||
DD | 84 (52.5%) | 35 (21.2%) | 34.3 | 0.000* | 4.1 (2.53–6.67) |
I | 84 (26.2%) | 210 (63.6%) | |||
D | 236 (73.8%) | 120 (36.4%) | 91.7 | 0.000* | 4.9 (3.52–6.87) |
AGT (M/T) | |||||
MM | 20 (12.5%) | 115 (69.7%) | |||
MT | 92 (57.5%) | 30 (18.2%) | |||
TT | 48 (30%) | 20 (12.1%) | 109.83 | 0.000* | |
MM | 20 (12.5%) | 115 (69.7%) | |||
MT + TT | 140 (87.5%) | 50 (30.3%) | 109.4 | 0.000* | 0.062 (0.035–0.11) |
MT + MM | 112 (70%) | 145 (87.9%) | |||
TT | 48 (30%) | 20 (12.1%) | 15.7 | 0.000* | 0.32 (0.18–0.57) |
M | 132 (41.2%) | 260 (78.8%) | |||
T | 188 (58.8%) | 70 (21.2%) | 95.6 | 0.000* | 0.19 (0.13–0.27) |
ARNT (G/A) | |||||
GG | 30 (18.7%) | 90 (54.6%) | |||
GA | 68 (42.5%) | 55 (33.3%) | |||
AA | 62 (38.8%) | 20 (12.1%) | 52.82 | 0.000* | |
GG | 30 (18.7%) | 90 (54.6%) | |||
GA + AA | 130 (81.3%) | 75 (45.4%) | 44.69 | 0.000* | 5.2 (3.15–8.6) |
GA + GG | 98 (61.2%) | 145 (87.9%) | |||
AA | 62 (38.8%) | 20 (12.1%) | 30.5 | 0.000* | 4.6 (2.6–8.1) |
G | 128 (40%) | 235 (71.2%) | |||
A | 192 (60%) | 95 (28.8%) | 64.2 | 0.000* | 3.7 (2.7–5.2) |