Table 3 Relation between various genotypes of the AGT (M/T) and risk factors among GDM and controls
Parameters | Genotype | MM + MT/TT | |||
|---|---|---|---|---|---|
M + SD | P value | ||||
Age (years) | Controls | 30.31 ± 3.96/31.50 ± 2.76 | 0.233/0.687 | ||
GDM | 29.56 ± 5.70/31.91 ± 5.61 | ||||
Duration (weeks) | Controls | 23.72 ± 3.83/23.25 ± 3.02 | 0.655/0.04* | ||
GDM | 23.96 ± 4.61/25.02 ± 3.21 | ||||
BMI (kg/m2) | Controls | 27.04 ± 4.74/26.36 ± 3.07 | 0.001*/0.001* | ||
GDM | 32.81 ± 7.78/32.99 ± 5.58 | ||||
Family history | Controls (No, Yes) n,% | 110 (75.9), 35 (24.1) | 10 (50.0), 10 (50.0) | 0.001* | 0.936 |
GDM (No, Yes) n,% | 44 (38.9), 69 (61.1) | 24 (51.1), 23 (48.9) | |||
Abortion history | Controls (No, Yes) n,% | 101 (69.7), 44 (30.3) | 15 (75.0), 5 (25.0) | 0.139 | 0.268 |
GDM (No, Yes) n,% | 88 (77.9), 25 (22.1) | 28 (60.9), 18 (39.1) | |||
Hypertension | Controls (No ,Yes) n,% | 140 (96.6), 5 (3.4) | 20 (100), 0 (0.0) | 0.021* | 0.003* |
GDM (No, Yes) n,% | 101 (89.4), 12 (10.6) | 31 (66.0), 16 (34.0) | |||
Glucose | Controls | 75.26 ± 6.53/70.50 ± 0.89 | 0.001*/0.001* | ||
GDM | 115.30 ± 50.27/120.53 ± 76.63 | ||||
HBA1c | Controls | 7.46 ± 1.65/7.23 ± 1.60 | 0.001*/0.534 | ||
GDM | 8.30 ± 1.80/7.91 ± 2.38 | ||||
Insulin | Controls | 10.40 ± 2.61/10.23 ± 1.58 | 0.001*/0.001* | ||
GDM | 36.36 ± 13.12/27.89 ± 12.33 | ||||
HOMA-IR | Controls | 1.93 ± 0.53/1.80 ± 0.32 | 0.001*/0.001* | ||
GDM | 9.90 ± 4.55/8.64 ± 7.44 | ||||