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Table 4 Relation between different genotypes of the ARNT (G/A) and risk factors among GDM and controls

From: Association of gene polymorphisms of ACE, AGT, and ARNT-like protein 1 with susceptibility to gestational diabetes

Parameters

Genotype

ARNT

(G/A)

GG+GA/AA

M+SD

P value

Age (years)

Controls

30.69 ± 3.90/28.63 ± 2.97

0.147/0.492

 

GDM

31.58 ± 5.22/27.91 ± 5.96

 

Duration (weeks)

Controls

23.48 ± 3.65/25.11 ± 4.12

0.016*/0.112

 

GDM

24.76 ± 4.38/23.41 ± 3.93

 

BMI (kg/m2)

Controls

26.88 ± 4.68/27.60 ± 3.69

0.001*/0.001*

 

GDM

32.25 ± 7.10/33.94 ± 7.27

 

Family history

Controls (No, Yes) n,%

105 (71.9), 41 (28.1)

15 (78.9), 4 (21.1)

0.001*

0.027*

 

GDM (No, Yes) n,%

39 (38.2), 63 (61.8)

29 (50), 29 (50)

 

Abortion history

Controls (No, Yes) n,%

102 (69.9), 44 (30.1)

14 (73.7), 5 (26.3)

0.451

0.802

 

GDM (No, Yes) n,%

75 (74.3), 26 (25.7)

41 (70.7), 17 (29.3)

 

Hypertension

Controls (No, Yes) n,%

145 (99.3), 1 (0.7)

15 (78.9), 4 (21.1)

0.001*

0.576

 

GDM (No, Yes) n,%

83 (81.4), 19 (18.6)

49 (84.5), 9 (15.5)

 

Glucose

Controls

75.22 ± 6.52/70.53 ± 0.91

0.001*/0.001*

 

GDM

111.50 ± 59.02/126.21 ± 58.37

 

HBA1c

Controls

7.37 ± 1.68/7.93 ± 1.28

0.001*/0.457

 

GDM

8.16 ± 2.00/8.22 ± 1.98

 

Insulin

Controls

10.38 ± 2.61/10.34 ± 1.54

0.001*/0.001*

 

GDM

33.75 ± 14.18/34.10 ± 12.11

 

HOMA-IR

Controls

1.93 ± 0.53/1.81 ± 0.32

0.001*/0.001*

 

GDM

9.06 ± 5.61/10.37 ± 5.42

 
  1. Data are presented as means ± standard deviation (SD)
  2. Bold values indicate significant difference
  3. *P ≤ 0.05 was considered significant