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Table 4 Crude and adjusted odds ratios for different levels of severity of SARS-CoV-2 infection according to the presence of the TNFα − 308.A allele by region

From: The role of tumor necrosis factor alpha − 308A > G polymorphism on the clinical states of SARS-CoV-2 infection

Characteristics

Symptomatic versus asymptomatic cases

Severe symptomatic versus non-severe symptomatic cases

Crude OR (95% CI)

Adjusted OR (95% CI)a

Crude OR (95% CI)

Adjusted OR (95% CI)a

Cuba

1.24 (0.91–1.70)

1.22 (0.89–1.68)

0.96 (0.51–1.79)

0.93 (0.49–1.75)

Eastern region

4.00 (0.86–18.66)

4.05 (0.84–19.43)

4.41 (1.14–17.05)

4.62 (1.11–19.26)

Central region

1.15 (0.68–1.93)

1.14 (0.67–1.95)

0.83 (0.27–2.57)

0.75 (0.23–2.42)

Western region

1.29 (0.84–1.99)

1.27 (0.82–1.98)

0.65 (0.25–1.73)

0.61 (0.23–1.64)

  1. aOR was adjusted for comorbidities such as hypertension, diabetes and obesity