A study of the genotyping and vascular endothelial growth factor polymorphism differences in diabetic and diabetic retinopathy patients

Egyptian Journal of Medical Human Genetics

Table 2 VEGF gene polymorphisms in NPDR patients and DWR

Polymorphisms	DWR group (n = 100)	NPDR group (n = 100)	OR (95% CI)	P-value
rs13207351 (− 152G > A)
Genotype
GG	9 (9%)	22 (22%)	3.01 (0.72–12.62)	0.141
GA	0 (0%)	14 (14%)	16.3 (0.80–331.7)	0.0074
AA	91 (91%)	64 (64%)	0.17 (0.04–0.65)	0.01
Allele
G	18 (9%)	58 (29%)	4.29 (1.62–11.37)	0.004
A	182 (91%)	142 (71%)	0.23 (0.09–0.61)
rs79469752 (− 165C > T)
Genotype
CC	89 (89%)	100 (100%)	0.16 (0.0086–3.099)	0.16
CT	9 (9%)	0 (0%)	0.27 (0.013–5.46)	0.54
TT	2 (2%)	0 (0%)	0.39 (0.018–8.41)	1
Allele
C	187 (93.5%)	200 (100%)	0.17 (0.009–3.23)	0.17
T	13 (6.5%)	0 (0%)	0.17 (0.009–3.23)	0.17

Data are expressed as number and percent, OR, odds ratio; CI, confidence interval, Fisher's exact test was performed to evaluate the statistical significant (P < 0.05), DWR, diabetic without retinopathy, NPDR, non-proliferative diabetic retinopathy, PDR, proliferative diabetic retinopathy