A study of the genotyping and vascular endothelial growth factor polymorphism differences in diabetic and diabetic retinopathy patients

Egyptian Journal of Medical Human Genetics

Table 3 VEGF gene polymorphisms in PDR patients and DWR

Polymorphisms	DWR group (n = 100)	PDR group (n = 100)	OR (95%CI)	P-value
rs13207351 (− 152G > A)
Genotype
GG	9 (9%)	28 (28%)	3.90 (1.05–14.48)	0.051
GA	0 (0%)	17 (17%)	20.43 (1.08–385.3)	0.0
AA	91 (91%)	55 (55%)	0.12 (0.03–0.42)	0.0005
Allele
G	18 (9%)	127 (63.5%)	18.06 (7.32–44.52)	0.001
A	182 (91%)	73 (36.5%)	0.05 (0.02–0.14)
rs79469752 (− 165C > T)
Genotype
CC	89 (89%)	100 (100%)	0.12 (0.007–2.348)	0.14
CT	9 (9%)	0 (0%)	0.205 (0.01–4.14)	0.27
TT	2 (2%)	0 (0%)	0.29 (0.014–6.37)	0.51
Allele
C	187 (93.5%)	200 (100%)	0.133 (0.007–2.45)	0.16
T	13 (6.5%)	0 (0%)	0.133 (0.007–2.45)	0.16

Data are expressed as number and percent, OR, odds ratio; CI, confidence interval, Fisher's exact test was performed to evaluate the statistical significant (P < 0.05), DWR, diabetic without retinopathy, PDR, proliferative diabetic retinopathy