Genotype | n | Hb A2 | MCV | MCH | ||||||
---|---|---|---|---|---|---|---|---|---|---|
Min; max | Mean | p value | Min; max | Mean | p value | Min; max | Mean | p value | ||
α-Thalassemia genotypes | 127 | 3.1; 3.9 | 3.23 ± 0.18 | 59.9; 102.5 | 75.87 ± 5.69 | 18.3; 32.5 | 24.22 ± 2.31 | |||
IVS-II-1 (G>A)/ W | 36 | 3.1; 3.9 | 3.70 ± 0.23 | < 0.0001 | 58.6; 76.4 | 64.73 ± 4.40 | < 0.0001 | 17.0; 24.7 | 19.86 ± 1.70 | < 0.0001 |
IVS-I-6 (T>C)/ W | 30 | 3.1; 3.9 | 3.71 ± 0.22 | < 0.0001 | 63.0; 78.2 | 69.28 ± 3.83 | < 0.0001 | 19.3;25.7 | 21.50 ± 1.45 | < 0.0001 |
Codons 8/9 (+G)/ W | 16 | 3.4; 3.9 | 3.73 ± 0.12 | < 0.0001 | 59.6; 67.6 | 63.20 ± 2.34 | < 0.0001 | 17.9; 21.1 | 19.04 ± 0.90 | < 0.0001 |
IVS-I-110 (G>A)/ W | 16 | 3.1; 3.9 | 3.72 ± 0.21 | < 0.0001 | 57.7; 69.5 | 64.53 ± 3.49 | < 0.0001 | 13.8; 21.8 | 19.46 ± 2.06 | < 0.0001 |
–101 (C > T)/W | 8 | 3.4; 3.9 | 3.68 ± 0.20 | < 0.0001 | 72.8; 88.0 | 79.68 ± 4.78 | 0.935 | 23.0; 27.7 | 26.11 ± 1.77 | 0.677 |
IVS-I-128 (T>G)/W | 8 | 3.5; 3.9 | 3.67 ± 0.15 | < 0.0001 | 68.0; 77.9 | 71.63 ± 3.52 | 0.870 | 20.4; 25.4 | 22.51 ± 1.58 | 0.806 |
Codons 36/37 (–T)/W | 7 | 3.2; 3.8 | 3.62 ± 0.20 | 0.001 | 62.0; 70.4 | 66.24 ± 3.42 | 0.005 | 19.1; 22.0 | 20.67 ± 1.05 | 0.007 |
IVS-I-1 (G>A)/ W | 4 | 3.7; 3.9 | 3.82 ± 0.09 | < 0.0001 | 61.3; 62.9 | 62.12 ± 0.71 | 0.001 | 18.0; 19.8 | 19.02 ± 0.75 | 0.001 |
Codons 82/83 (–G)/ W | 4 | 3.2; 3.8 | 3.62 ± 0.28 | 0.078 | 53.1; 64.5 | 59.15 ± 4.77 | < 0.0001 | 16.2; 19.8 | 18.35 ± 1.60 | < 0.0001 |
Coexistence of α- and β-thalassemia genotypes | 5 | 3.2; 3.7 | 3.40 ± 0.21 | 0.980 | 68.1; 79.0 | 72.9 ± 4.18 | 1.000 | 20.1; 25.4 | 22.62 ± 2.22 | 0.985 |