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Table 5 Comparison of mean values of Hb A2, MCV and MCH in β-thalassemia genotypes (as a single group) with those in α-thalassemia genotypes identified in this study

From: Problem of borderline hemoglobin A2 levels in an Iranian population with a high prevalence of α- and β-thalassemia carriers

Genotype

n

Hb A2

MCV

MCH

Min; max

Mean

p value

Min; max

Mean

p value

Min; max

Mean

p value

β-Thalassemia genotypes

150

3.1; 3.9

3.71 ± 0.20

 

51.0; 88.0

66.66 ± 5.82

 

13.0; 27.7

20.54 ± 2.42

 

αα/-α

69

3.1; 3.8

3.21 ± 0.16

 < 0.0001

67.0; 102.5

78.27 ± 4.67

 < 0.0001

20.8; 32.5

25.32 ± 1.64

 < 0.0001

-α/-α

18

3.1; 3.9

3.28 ± 0.25

 < 0.0001

63.0; 74.0

69.22 ± 3.10

0.645

19.1;23.9

21.25 ± 1.37

0.896

αα/–

4

3.1; 3.5

3.25 ± 0.19

 < 0.0001

66.9; 72.4

68.97 ± 2.60

0.991

20.6; 21.9

21.37 ± 0.55

0.993

αα/αNDα or αα/ααND

36

3.1; 3.9

3.23 ± 0.19

 < 0.0001

59.9; 87.1

75.35 ± 5.39

 < 0.0001

18.3; 27.6

23.91 ± 2.25

 < 0.0001

Coexistence of α- and β-thalassemia genotypes

5

3.2; 3.7

3.40 ± 0.21

0.047

68.1; 79.0

72.9 ± 4.18

0.372

20.1; 25.4

22.62 ± 2.22

0.566

  1. ND, non-deletional