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Table 1 Demographical and clinical characteristics of endometriosis patients and controls

From: Increased expression of IL-37 correlates with TNF-α levels and disease stage in endometriosis patients

  Endometriosis patients (n = 50) Controls (n = 23)
Age in years, mean ± SD 29.7 ± 6.2 30.9 ± 5.1
Parity, n (%)   
 P0 38 (76%) 15 (65.2%)
 P1 6 (12%) 5 (21.7%)
 P2 6 (12%) 3 (13.1%)
rAFS score for endometriosis, median (IQR) 14 (10–26) NA
rAFS stage for endometriosis, n (%)   
 Stage I 7 (14%) NA
 Stage II 19 (38%)  
 Stage III 19 (38%)  
 Stage IV 5 (10%)  
Serum IL-37 (pg/mL), median (IQR) 128.1 (93.9–198.7) 64.6 (52.7–94.3)
Peritoneal fluid IL-37 (pg/mL), median (IQR) 146.2 (106.1–194.4) 75.5 (61.8–108.2)
IL-37 mRNA expression, (2−ΔCT) 0.0239 (0.01393–0.03218) 0.0029 (0.0017–0.0052)
Peritoneal fluid TNF-α (pg/mL), median (IQR) 55.55 (39.7–63.5) 15.6 (12.8–19.3)
  1. IQR interquartile range, NA not applicable, rAFS revised American Fertility Society