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Table 1 Characteristics of the study subjects

From: Fibroblast growth factor-23 rs7955866 polymorphism and risk of chronic kidney disease

Parameter

CKD patients (N = 72)

Controls (N = 26)

Statistical test

P value

Male

35 (48.6%)

14 (53.8%)

Chi-square

0.647

Female

37 (51.4%)

12 (46.2%)

  

Age (Y)

48 (38.8–59.3)

43 (36.5–52)

MWU

0.179

S. Creatinine (mg/dL)

1.5 (1.2–1.9)

0.9 (0.7–1)

MWU

 < 0.001**

GFR-EPI (mL/min/1.73)

44 (35.3–61.5)

95.5 (81.3–112)

MWU

 < 0.001**

Proteinuria (gm/day)

2.1 (1.2–4)

0.1 (0.1–0.1)

MWU

 < 0.001**

S. Urea (mg/dL)

81.44 ± 20.6

27.77 ± 5.9

TT

 < 0.001**

S. Uric Acid (mg/dL)

7.39 ± 2.4

5.08 ± 1.2

TT

 < 0.001**

S. Proteins (gm/dL)

6.4 (5.7–6.9)

6.9 (6.4–7.1)

MWU

 < 0.001**

S. Albumin (gm/dL)

3.2 (2.6–3.5)

3.9 (3.7–4.1)

MWU

 < 0.001**

S. Calcium (mg/dL)

9.09 ± 0.9

9.35 ± 0.6

TT

0.105

S. Phosphorus (mg/dL)

4.88 ± 1

3.5 ± 0.3

TT

 < 0.001**

S. iPTH (pg/mL)

160.5 (100–202.5)

41.5 (30–48)

MWU

 < 0.001**

S. Vitamin D3 (ng/mL)

14.8 (12–22)

35.2 (29.3–38.2)

MWU

 < 0.001**

S. iFGF23 (pg/mL)

729.2 (531.9–972.3)

126.1 (88.5–152.4)

MWU

 < 0.001**

Hemoglobin (gm/dL)

10.2 (9.4–11.3)

13.1 (12.9–14.3)

MWU

 < 0.001**

WBCs (k/uL)

7.5 (5.9–9.3)

5.9 (4–7.1)

MWU

 < 0.001**

Platelets (k/uL)

296.63 ± 74.7

320.81 ± 39.8

TT

0.043*

  1. CKD, chronic kidney disease; S., serum; GFR-EPI, estimated glomerular filtration rate by CKD epidemiology collaboration equation; iPTH, intact parathyroid hormone; iFGF23, intact fibroblast growth factor 23; WBCs, white blood cells; k, one thousand; MWU, Mann–Whitney U test; TT, independent sample t-test
  2. Data are expressed as either mean ± SD or median (interquartile range), *: significant (P < 0.05), **: highly significant (P < 0.01)