Table 3 Location, genetic code change, and effect on amino acid sequence in patients with PCOS
Location of genetic change in the AR gene | Change in genetic code | Change in amino acid | Change of chemical criteria |
|---|---|---|---|
X:67545218 | GAA > CAA | E (Glu) > Q (Gln) | Acidic to polar |
X:67545264 | AGG > TGG | R (Arg) > W (Trp) | Basic to non-polar |
X:57545509 | GGC > GCC | G (Gly) > A (Ala) | Polar–polar |
X:67545583 | CCG > CAG | P (Pro) > Q (Gln) | Non-polar to polar |
X:67545633 | ACG > TCG | T (Thr) > S (Ser) | Polar–polar |
X:67545672 | AGC > ACA | S (Ser) > T (Thr) | Polar–polar |
X:67545673 | AGC > TGC | S(Ser) > C (Cys) | Non-polar to Non-polar |