Comparative frequency distribution of glutathione S-transferase mu (GSTM1) and theta (GSTT1) allelic forms in Himachal Pradesh population

Egyptian Journal of Medical Human Genetics

Table 2 Overall distributions of GSTT1 and GSTM1 genotypes according to gender in the Himachal Population

Gender	No (%)	GSTM1 N (%)		P value OR (CI 95%)	GSTT1 N (%)		P value OR (CI 95%)	GSTM1 + T1 N (%)		P value OR (CI 95%)
Gender	No (%)	Null	Non-null	P value OR (CI 95%)	Null	Non-null	P value OR (CI 95%)	Null	Non-null	P value OR (CI 95%)
Males	232 (78)	76 (32.8)	156 (67.2)	p > 0.05	77(33.2)	155(68.8)	p > 0.05	25(10.8)	107(46.2)	p > 0.05
				1.12			0.77			0.31
Females	65 (22)	23 (35.4)	42 (64.6)	(0.63–2.00)	18(27.7)	47(72.3)	(0.42–1.41)	2 (3.07)	27(41.5)	(0.07–1.42)
Total	297 (100)	99 (33.3)	198 (66.7)		95 (32)	202 (68)		27 (9%)	134 (45.1)

Fisher’s exact test was used for comparison of gene frequency between male and female participants. No significant differences were observed (p > 0.05).CI- Class Interval, OD- Odd ratio, Null genotype is representing homozygous deletion (absence of both alleles)