Table 2 The relation between genotype and allele frequency distribution of PD-1 and PDL-1 in T1DM and control subjects
Variable | Patients (TIDM) N (%) | Control N (%) | Adjusted OR | 95%CI | p value |
|---|---|---|---|---|---|
PD-1 rs34819629 | |||||
GG | 80 (100%) | 76 (100%) | – | ||
GA | – | – | |||
CC | – | – | – | ||
PDL-1rs4143815 | |||||
Genotypes | |||||
CC | 2 (2.5%) | 4 (5.3%) | 0.123 | ||
CG | 30 (37.5%) | 32 (42.1%) | |||
GG | 48 (60.0%) | 40 (52.6%) | |||
Allele | |||||
C | 34 (21.25%) | 40 (26.3%) | 1.675 | 0.957–2.934 | 0.071 |
G | 126 (78.75%) | 112 (73.7%) | |||
PDL-1 rs2297137 | |||||
Genotypes | |||||
AA | 2 (2.5%) | 4 (5.3%) | 0.018 | ||
GA | 24 (30.0%) | 28(36.8%) | |||
GG | 54 (67.5%) | 44 (57.9%) | |||
Allele | |||||
A | 28 (17.5%) | 36 (23.7%) | 2.523 | 1.325–4.802 | 0.005 |
G | 132 (82.5%) | 116 (76.3%) |