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Table 4 Different genetic models regarding hemoglobin A1c & urinary albumin/ creatinine ratio

From: The genetic influence of PD-1/PD-L1 axis single nucleotide polymorphisms on the incidence of type 1 diabetes mellitus in pediatric Egyptian patients

Variable

 

Model type

HbA1c

UACR

(Good glycemic control) ≤ 7.0%

(Poor glycemic control) > 7%

 < 30 mg/g creatinine (Normal)

 ≥ 30 mg/g creatinine (Abnormal)

PDL-1 rs4143815

General genetic model

CC

2

0

2

0

CG

24

6

24

6

GG

20

28

38

10

p value

  

Dominant genetic model

CC

2

0

2

0

CG + GG

44

34

62

16

p value

  

Recessive genetic model

GG

20

28

38

10

CC + GC

60

6

26

6

p value

 < 0.001

 < 0.819

  

PDL-1 rs2297137

General genetic model

AA

2

0

2

0

GA

20

4

20

4

GG

24

30

42

12

p value

  

Dominant genetic model

AA

2

0

2

0

GA + GG

44

34

62

16

p value

  

Recessive genetic model

GG

24

30

42

12

AA + GA

22

4

22

4

p value

0.001

0.474

  
  1. UACR, urinary albumin/creatinine ratio; rs, recognition site; PDL-1, programmed death-ligand 1
  2. Bold values indicate the p-value < 0.01 is highly significant