Table 2 Laboratory investigations of studied groups
Parameters | Mixed complications N = 26 | Control N = 26 | Test | P value |
|---|---|---|---|---|
FBG (mg/dl) | t = | |||
Mean ± SD | 298.0 ± 74.3 | 85.6 ± 15.6 | 14.27 | < 0.001 |
Median (range) | 297.5 (145–440) | 88 (18–100) | ||
HbA1c % | t = | |||
Mean ± SD | 8.9 ± 1.3 | 5.0 ± 0.6 | 14.19 | < 0.001 |
Median (range) | 8.7(6.9–12.8) | 5.0 (4–6) | ||
Cholesterol (mg/dl) | t = | |||
Mean ± SD | 205.7 ± 26.4 | 153.5 ± 21.2 | 7.87 | < 0.001 |
Median (range) | 200 (159–270) | 155.5 (110–180) | ||
TG (mg/dl) | t = | |||
Mean ± SD | 134.2 ± 17.8 | 124.0 ± 22.9 | 1.79 | 0.08 |
Median (range) | 136.5(73–150) | 121(100–190) | ||
HDL-c (mg/dl) | t = | |||
Mean ± SD | 37.5 ± 2.2 | 40.3 ± 4.0 | 3.05 | 0.004 |
Median (range) | 37 (35–43) | 40 (34–53) | ||
LDL-c (mg/dl) | t = | |||
Mean ± SD | 135.5 ± 25.3 | 98.2 ± 10.3 | 6.97 | < 0.001 |
Median (range) | 133 (106–208) | 101(69–112) | ||
ACR (mg/gm creatinine) | ||||
Mean ± SD | < 0.001 | |||
Mean ± SD | 730.1 ± 285.5 | 14.9 ± 4.9 | U = | |
Median (range ) | 781 (110–1150) | 14.5(7–23) | 6.19 | |
Creatinine (mg/dl) | ||||
Mean ± SD | 4.7 ± 2.5 | 0.88 ± 0.12 | U = | < 0.001 |
Median (range) | 5.55 (0.9–10) | 0.90 (0.6–1.1 | 5.92 | |
BUN (mg/dl) | U = | |||
Mean ± SD | 56.0 ± 17.3 | 13.1 ± 3.8 | < 0.001 | |
Median (range) | 62 (11–71) | 12.5 (8–20) | 5.6 | |
Uric acid (mg/dl) | t = | |||
Mean ± SD | 7.4 ± 1.8 | 4.5 ± 1.2 | 6.88 | < 0.001 |
Median (range) | 12.6 (3.5–9.6) | 4.65 (2.7–6.5) | ||
eGFR (ml/min/1.73m2) | U = | < 0.001 | ||
Mean ± SD | 20.5 ± 24.5 | 100.2 ± 13.0 | ||
Median (range) | 7.9 (5.3–99.2) | 4.65 (71.9–133.7) | 5.92 | |
VEGF-A (pg/ml) | ||||
Mean ± SD | 229.1 ± 279.1 | 139.0 ± 61.0 | U = | 0.003 |
Median (range) | 132.5 (60–1350) | 117.5 (66–290) | 4.53 |