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Table 5 Relationship between VEGF-A rs3025020 and rs3025039 genotypes and different studied parameters in control group

From: Vascular endothelial growth factor A with two genetic variants for prediction of mixed microvascular diabetic complications

Control group

rs3025020 genotypes

rs3025039 genotypes

CC

N = 18

CT

N = 8

P value

CC

N = 20

CT& TT

N = 6

P value

Parameters

Mean ± SD

Mean ± SD

U

Mean ± SD

Mean ± SD

U

Age (years)

59.78 ± 5.22

61.5 ± 2.83

0.40

61.1 ± 4.13

57.66 ± 5.61

0.18

FBG (mg/dl)

86.44 ± 18.5

83.62 ± 5.45

0.09

85.95 ± 17.60

84.33 ± 5.92

0.24

HbA1c %

4.93 ± 0.50

5.28 ± 0.67

0.16

5.05 ± 0.55

5.0 ± 0.69

0.98

Cholesterol (mg/dl)

152.94 ± 24.27

154.27 ± 12.81

0.81

156.15 ± 18.33

144.67 ± 28.95

0.46

TG (mg/dl)

126.61 ± 25.35

118.13 ± 16.19

0.46

124.35 ± 24.93

122.83 ± 16.42

0.88

HDL-C (mg/dl)

41.05 ± 4.14

38.5 ± 3.29

0.14

40.85 ± 4.26

38.33 ± 2.42

0.16

LDL-C (mg/dl)

98.0 ± 11.32

98.63 ± 8.07

0.77

96.20 ± 10.74

104.83 ± 4.44

0.051

ACR (mg/gm creatinine)

14.82 ± 5.05

14.99 ± 4.79

0.98

15.10 ± 4.45

14.12 ± 6.54

0.66

Creatinine (mg/dl)

0.87 ± 0.14

0.90 ± 0.08

0.57

0.88 ± 0.11

0.87 ± 0.18

0.88

BUN (mg/dl)

13.56 ± 3.91

12.13 ± 3.40

0.34

13.25 ± 3.63

12.67 ± 4.50

0.53

Uric acid (mg/dl)

4.54 ± 1.23

4.44 ± 1.15

0.85

4.63 ± 1.24

4.12 ± 0.98

0.39

eGFR (ml/min/1.73 m2)

100.07 ± 14.41

100.36 ± 9.91

0.89

98.55 ± 12.27

105.5 ± 15.07

0.49

VEGF-A (pg/ml)

150.5 ± 66.99

113.13 ± 36.07

0.24

134.2 ± 58.66

155.0 ± 71.76

0.42

  1. U Mann–Whitney test, FBS fasting blood sugar, HbA1c hemoglobin A1C, TG triglyceride, LDL-C low-density lipoprotein cholesterol, HDL-C high-density lipoprotein cholesterol, BUN blood urea nitrogen, ACR albumin/creatinine ratio, eGFR estimated glomerular filtration rate, VEGF-A vascular endothelial growth factor A