SNP ID | Nucleotide substitution | Amino acid change | SIFT result | SIFT score | PolyPhen-2 result | PolyPhen-2 score | PROVEAN result (cut-off = − 2.5) | PROVEAN score | PhD-SNP result | PhD-SNP RI | PMut result | PMut score |
---|---|---|---|---|---|---|---|---|---|---|---|---|
rs111838634 | T/C | K106E | DEL | 0.005 | Pro-damg | 0.999 | DEL | − 3.667 | Diseased | 5 | Neutral | 0.26 |
rs112362579 | A/T | I158N | DEL | 0.001 | Pro-damg | 0.973 | DEL | − 6.254 | Diseased | 6 | Diseased | 0.83 |
rs139778919 | A/G | L112P | DEL | 0.001 | Pro-damg | 1.000 | DEL | − 6.831 | Diseased | 6 | Diseased | 0.83 |
rs141717616 | G/A | P125S | DEL | 0 | Pro-damg | 1.000 | DEL | − 7.960 | N | 4 | Diseased | 0.64 |
rs146901447 | G/A | P162L | DEL | 0.002 | Pro-damg | 1.000 | DEL | − 9.850 | Diseased | 8 | Neutral | 0.28 |
rs147661457 | G/T | H61Q | DEL | 0 | Pro-damg | 1.000 | DEL | − 7.782 | Diseased | 3 | Neutral | 0.49 |
rs148039766 | G/T | A128E | DEL | 0.001 | Pro-damg | 1.000 | DEL | − 4.975 | N | 3 | Diseased | 0.80 |
rs148775490 | C/T | G81R | DEL | 0.002 | Pro-damg | 1.000 | DEL | − 7.167 | Diseased | 5 | Diseased | 0.83 |
rs199674976 | G/T | A298D | DEL | 0.004 | Pro-damg | 0.991 | DEL | − 4.380 | Diseased | 7 | Neutral | 0.28 |
rs373244724 | T/C | Y273C | DEL | 0 | Pro-damg | 1.000 | DEL | − 8.066 | Diseased | 4 | Neutral | 0.40 |
rs374762995 | A/C | V118G | DEL | 0.001 | Pro-damg | 0.973 | DEL | − 6.865 | Diseased | 4 | Diseased | 0.80 |