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Table 1 Delta G value obtained from the molecular interaction of selected cancer receptors with respective control and curcumin analogues

From: Identifying the potential role of curcumin analogues as anti-breast cancer agents; an in silico approach

Sl. No.

Ligand

Delta G (kcal/mol)

  

FGF

MMP9

RNRM1

TGF-β

VEGF

DHFR

Aromatase

1

Control

− 2.15

− 3.57

− 3.27

− 4.5

− 2.69

− 2.73

− 4.06

2

Capsaicin

0.08

− 0.63

− 0.02

0.48

1.87

− 0.03

0.15

3

Chlorogenic acid

− 1.74

− 3.02

− 2.07

− 0.99

− 2.01

− 1.54

− 2.12

4

Ferulic acid

− 0.99

− 3.68

− 2.81

− 1.19

− 1.54

− 1.68

− 2.46

5

Gingerol

− 0.42

− 1.99

− 0.73

0.09

0.71

− 1.21

− 0.16

6

Zingerone

− 1.08

− 1.91

− 2.13

− 1.07

− 0.86

0.36

− 1.51