Fig. 2From: Understanding the pivotal roles of ACE2 in SARS-CoV-2 infection: from structure/function to therapeutic implicationACE2 structure and its function in the renin–angiotensin–aldosterone system (RAAS). A ACE2 structure; N-terminal domain includes single peptide, protein cleavage site, and active site and C-terminal domain contain transmembrane alpha-helix. B Schematic overview of ACE2 functions in the renin–angiotensin–aldosterone system (RASS)Back to article page