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Fig. 2 | Egyptian Journal of Medical Human Genetics

Fig. 2

From: Generation of muscle progenitors from human-induced pluripotent stem cells

Fig. 2

Givinostat has dual expression of cardiac/skeletal myogenic genes: GIV increased upregulation of cardiac/skeletal myogenic genes (Real Time PCR Assay) versus ISX9, DAN and control after 7 days. A Muscle genes included Myf5, Pax7, MyoD1, myogenin, dystrophin, desmin and β-catenin. B Cardiac gene included Isl1, Nkx2.5, Tbx5, GATA4, Mef2c, Myh6 and Mlc2v. Values are mean ± SE; n = 3; P-value < 0.05, * P-value = 0.01, ** P-value = 0.001, # P-value = 0.0001 are significant

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