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Table 4 Genotypic and allelic frequencies of FactorVG1691A, MTHFRC677T and Factor XIII V34L polymorphisms in AMI patients and control group

From: Association of factor V Leiden R506Q, FXIIIVal34Leu, and MTHFR C677T polymorphisms with acute myocardial infarction

Polymorphisms

Genotype

Control, n (%)

Case, n (%)

P

OR

95% CI

Control P′ HWE

FVLG1691A

GG

149 (99.3)

144 (96)

1

  

0.96

 

GA

1 (0.7)

5 (3.3)

0.13

5.17

0.59–44.8

 
 

AA

0 (0.0)

1 (0.7)

0.99

1.6

0.00

 

Allele

       

 G

 

299 (99.7)

293 (97.7)

1

   

 A

 

1 (0.3)

7 (2.3)

0.068

0.14

0.017–1.145

 

MTHFRC677T

CC

88 (58.7)

69 (46)

1

  

0.66

 

CT

55 (36.7)

74 (49.3)

0.02*

1.76

1.07–2.75

 
 

TT

7 (4.7)

7 (4.7)

0.66

1.27

0.43–3.81

 

Allele

       

 C

 

231 (77)

212 (70.7)

1

   

 T

 

69 (23)

88 (29.3)

0.08

1.39

0.96–2.00

 

Factor XIIIV34L

GG

102 (68)

103 (68.7)

1

  

0.85

 

GT

43 (28.7)

46 (30.7)

0.82

1.059

0.64–1.74

 
 

TT

5 (3.3)

1 (0.7)

0.13

0.19

0.02–1.68

 

Allele

       

 G

 

247 (82.3)

252 (84)

1

   

 T

 

53 (17.7)

48 (16)

0.58

0.88

0.57–1.36

 
  1. AMI, acute myocardial infarction; OR, odds ratio; CI, confidence interval; HWE, Hardy–Weinberg equilibrium; The OR reference of genotypes and alleles is 1 (GG genotype and G allele for the FVL G1691A polymorphism, CC and C for MTHFR C677T, and GG and G for Factor XIIIV34L)
  2. *Statistically significant P-value < 0.05