All patients n = 90 F:26, M:64 | Moderate n = 19 F:5, M:14 | Severe n = 71 F:21, M:50 | P-value* | Hypertension n = 70 | Non hypertensive | P-value* | CVD n = 40 | P-value* | DM n = 22 | P-value* | |||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Gene allele* | |||||||||||||
G | 82 (70.7%) | 8 (33.3%) | 74 (80.4%) | 0.000 | 73 (79.3%) | 9 (37.5%) | 0.000 | 33 (70.2%) | 49 (71.0%) | 0.924 | 22 (81.5%) | 60 (67.4%) | 0.160 |
T | 34 (29.3%) | 16 (66.7%) | 18 (19.6%) | 19 (20.7%) | 15 (62.5%) | 14 (29.8%) | 20 (29.0%) | 5 (18.5%) | 29 (32.6%) | ||||
rs2048683 genotype | |||||||||||||
GG/G | 59 (65.6%) | 3 (15.8%) | 56 (78.9%) | 0.000 | 53 (75.7%) | 6 (30.0%) | 0.001 | 28 (70.0%) | 31 (62.0%) | 0.047 | 17 (77.3%) | 42 (61.8%) | 0.282 |
GT | 7 (7.8%) | 5 (26.3%) | 2 (2.8%) | 4 (5.7%) | 3 (15.0%) | 0 (0.0%) | 7 (14.0%) | 2 (9.1%) | 5 (7.4%) | ||||
TT/T | 24 (26.7%) | 11 (57.9%) | 13 (18.3%) | 13 (18.6%) | 11 (55.0%) | 12 (30.0%) | 12 (24.0%) | 3 (13.6%) | 21 (30.9%) | ||||
rs2048683 genotype in females | |||||||||||||
GG | 16 (17.8%) | 0 (0.0%) | 16 (22.5%) | 0.000 | 16 (22.9%) | 0 (0.0%) | 0.021 | 5 (12.5%) | 11 (22.0%) | 0.077 | 3 (13.6%) | 13 (19.1%) | 0.574 |
GT | 7 (7.8%) | 5 (26.3%) | 2 (2.8%) | 4 (5.7%) | 3 (15.0%) | 0 (0.0%) | 7 (14.0%) | 2 (9.1%) | 5 (7.4%) | ||||
TT | 3 (3.3%) | 0 (0.0%) | 3 (4.2%) | 2 (2.9%) | 1 (5.0%) | 2 (5.0%) | 1 (2.0%) | 0 (0.0%) | 3 (4.4%) | ||||
rs2048683 genotype in males | |||||||||||||
G | 43 (47.8%) | 3 (15.8%) | 40 (56.3%) | 0.000 | 37 (52.9%) | 6 (30.0%) | 0.003 | 23 (57.5%) | 20 (40.0%) | 0.659 | 14 (63.6%) | 29 (42.6%) | 0.120 |
T | 21 (23.3%) | 11 (57.9%) | 10 (14.1%) | 11 (15.7%) | 10 (50.0%) | 10 (25.0%) | 11 (22.0%) | 3 (13.6%) | 18 (26.5%) |