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Egyptian Journal of Medical Human Genetics

Table 2 Alleles frequency distribution of Tamoxifen metabolizing enzyme

From: Influence of CYP2D6, CYP2C19 and CYP3A5 polymorphisms on plasma levels of tamoxifen metabolites in Algerian women with ER+ breast cancer

CYP2D6

Frequency

Value (%)

CYP2D6*1, CYP2D6*2 > 2 copies

32

33.03

CYP2D6*1

14

14.40

CYP2D6*2

32

33.03

CYP2D6*5

1

1.03

CYP2D6*10

2

2.06

CYP2D6*17

6

6.18

CYP2D6*35

1

1.03

CYP2D6*39

1

1.03

CYP2D6*41

8

8.25

CYP2C192C19 CYP2C19

 

Value

CYP2C19*1

86

93.40

CYP2C19*2

5

5.52

CYP2C19*17

1

1.08

CYP3A53A5 CYP3A5

 

Value

CYP3A5*1

22

22.68

CYP3A5*3

74

76.29

CYP3A5*6

1

1.03

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