Egyptian Journal of Medical Human Genetics

Table 6 Plasma concentrations of Endoxifen in subjects with CYP2D6, CYP2C19 and CYP3A5 genotype

From: Influence of CYP2D6, CYP2C19 and CYP3A5 polymorphisms on plasma levels of tamoxifen metabolites in Algerian women with ER⁺ breast cancer

CYP2D6 CPIC phenotype	(N = 97)	Endoxifen (ng/mL) median
URM	32	94.19
NM	48	69.13
IM	16	29.40
PM	1	4.40
CYP3A5 CPIC phenotype	(N = 97)	Endoxifen (ng/mL) median
NM	3	114.31
IM	24	90.92
PM	70	70.88
CYP2C19 CPIC phenotype	(N = 97)	Endoxifen (ng/mL) median
URM	1	88.70
RM	30	60.53
NM	49	71.77
IM	10	47.34
PM	2	45.60

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